March 2001
- March 14, 2001
- Double Trouble, Meatloaf, The Alchemysts, The Caribbean, Lovewhip, The Lisa Marr Experiment, White Willow
- March 25, 2001
- SXSW 2001, Evelyn Forever, Steve Almaas, Daniel Christopherson, Flogging Molly, Delbert McClinton, Miss Fortune, Adrian Shaw, Rodney Crowell, Ray Paul
April 2001
- April 1, 2001
- Nick Saloman, Bevis Frond, Acid Jam, Pinkston, The Beauty Shop, Jim Greer, Ingo Star Cruiser, Amy Ray, Tugboat Annie, Twin Princess, Kris Kristofferson, The Psychedelic Furs
- April 8, 2001
- Nusrat Fateh Ali Khan, Rahat Nusrat Fateh Ali Khan, John Cale, Joe Maphis, Charlie Rich, Cosmic Rough Riders, Electric Frankenstein, Gravy Boat, Ice Age, Idlewild, Malkum Gibson, Chris Kleeman, Jennifer Marks, Paved Country, Turbonegro
- April 22, 2001
- Joey Ramone tributes, The BellRays, Acumen, The Flyte Reaction, Hamell on Trial, Metroscene, The Mother Hips, Rhythm of Black Lines, Sunday Flood, Scorched Earth, The Volebeats, Matthew Smith, Jeff Oakes, Leatherface, The O'Jays
- April 29, 2001
- More Joey Ramone tributes, The Streetwalkin' Cheetahs, The Dave Brubeck Quartet, Clutch, Gnappy, Will Hoge, Greg Panfile & Talk & Roll, Son of Sam, Zero Hour, The Chamber Strings
May 2001
- May 6, 2001
- Nick Cave and the Bad Seeds, Femi Kuti and Positive Force, Karl Denson's Tiny Universe, The Chamber Strings, Charles Curtis, Kevin Deal, Monster Magnet, Shadow Gallery, The George Usher Group, Wayne Kramer
- May 13, 2001
- Wilson "Boozoo" Chavis tribute, Cheap Trick, Widespread Panic, Olu Dara, The Fletcher Pratt, Moods for Moderns, The Mullens, Tempest, Garmarna, Hedningarna
- May 20, 2001
- Earth, Wind and Fire, Maurice White, Savatage, Fates Warning, Adolfo's Reversal, Calendar Girl, Johnny Dowd, The Green Pajamas, The Lovelight Shine, Saga, Soulfarm, Värttinä, The Shoes
- May 27, 2001
- Alejandro Escovedo, Shuggie Otis, David Andrews, The Continental Drifters, Fireking, Gore Gore Girls, The Prayer Boat, Swag
June 2001
- June 3, 2001
- Amorphis, Katatonia, Opeth, The Green Pajamas, Attention Deficit, Hayseed Dixie, Mother Superior, The Other 99, Amanda Thorpe
- June 10, 2001
- Fargo Rock City, Miles Davis, Danny Barnes, Thee Old Codgers, Jack Breakfast, The Morells, Tracy Nelson, Johnny Polonsky
- June 17, 2001
- Buddy Guy, Worst of the 80s, Kansas, Jack & the Beanstalk, Scott Miller & the Commonwealth, Neatbeats, Patti Rothberg, Blessed By the Night
- June 24, 2001
- John Lee Hooker tributes, Chris Whitley, Air, Robert Berry, Doyle Bramhall, Scott McGill, Michael Manring, Vic Stevens, Rainravens, Judas Priest
July 2001
- July 1, 2001
- Nikolo Kotzev, Trent Gardner, Miles Davis, Gun Barrel, The Irving Klaws, Adam Schmitt, Whiskeytown, Lucinda Williams, Steve Earle
- July 8, 2001
- Mark Eitzel, Tempest, Bicycle Thief, Electric Light Orchestra, Lucyfire, Rufus Wainwright, M. Ward
- July 15, 2001
- Richard Thompson, Electric Light Orchestra, God Forbid, Porcupine Tree, Scooters, Shaver, Otis Taylor, Mark Eitzel
- July 22, 2001
- Blue Öyster Cult, Tony Hill, Mellow, Mint, The Pee Wee Fist, Rosa Chance Well
- July 29, 2001
- Pernice Brothers, Roots of Rhythm with Harry Belafonte DVD, Acid Mothers Temple, Edenbridge, Maria Kalaniemi, Sven Ahlbäck, Kelly Joe Phelps, Trash Wednesday, Billy Bremner, Dan Hicks
August 2001
- August 5, 2001
- Robert Cray, David Menconi, Blackmore's Night, Tom Freund, Fred Koller, thebrotheregg, Miles Davis, John Coltrane
- August 26, 2001
- Varnaline, Mahalia Jackson, Autoliner, David Mead, Spirit Caravan, Karen Tweed, Timo Alakotila, Alex Woodward, Del McCoury Band
September 2001
- September 2, 2001
- Critiquing the Critics editorial, Radney Foster, Cairo, Kittymonkey, Lost Kids, Del McCoury Band, Carlos Santana, Bill Laswell, George Benson Quartet
- September 9, 2001
- Sigh, Radio Birdman, Robin Eubanks and Mental Images, Gary Myrick, Graham Parker, Iggy Pop, Tool
- September 16, 2001
- The Soundtrack of Our Lives, Bob Dylan: Don't Look Back DVD, Sean Croghan, Greg Osby, Grant-Lee Phillips, Gonzalo Rubalcaba, Sugarcult, King Crimson
- September 23, 2001
- Richard Buckner, Anders Parker, Words and Music of WWII, Michael Lee Firkins, Chris McFarland, Rock City Crimewave, Erik Truffaz, Charlie Patton, The Residents
- September 30, 2001
- Rollins Band, Ben Folds, The Damned, Garmarna, John Hiatt, Hum Machine, Transatlantic, Gladys Knight and the Pips, Molly Hatchet
October 2001
- October 7, 2001
- Hedwig and the Angry Inch movie review, Harold Melvin & the Blue Notes, Pat Haney, James LaBrie's Mullmuzzler, Madredeus, Pat Martino, Quasi, Michael Rank
- October 14, 2001
- Al Kooper, The Wild Seeds, Wannabes, Rite Fliers, Libbi Bosworth, Hoven Droven, Frank Marino & Mahogany Rush, The Moto-Litas, Loudon Wainwright III
- October 21, 2001
- maudlin of the Well, Velvet Crush, Bodyjar, DFA, Hank Harris, Dave Holland Quintet, Hedwig and the Angry Inch soundtrack
- October 28, 2001
- Simon and Garfunkel, Fugu, Jason Moran, Darryl Purpose, Rabies Caste, TSOL, Tenacious D
November 2001
- November 4, 2001
- Ryan Adams, Jay Farrar, Chris Knight, Freedy Johnston, Rose Polenzani, Cousteau, Jennifer Daniels, Finisterre, Jackie King, Moonspell, Pope Syndicate, The Rembrandts, The Waterboys
- November 11, 2001
- Billie Holiday, The Damned, The Toilet Boys, The Briefs, The Grip Weeds, Duane Jarvis, Mortiis, 16 Horsepower, Solarized, Somnambulist, Bill Ware, Sonic Cinema: "Video to Screen" and "Animators"
- November 18, 2001
- Sparklehorse, Sonic Cinema: "Sparklehorse," Demolition String Band, Fu Manchu, Nick Lowe, Mad for the Racket, Munk, The Strokes, Dallas Wayne, Kim Wilson, The Orange Alabaster Mushroom
- November 25, 2001
- Drive-By Truckers, Stevie Ray Vaughn and Double Trouble, Finntroll, Terry Garland, Money Mark, The Silos, Ricky Skaggs and Kentucky Thunder, Star City, Ken Stringfellow, The Thrillbillys soundtrack
December 2001
- December 2, 2001
- George Harrison tribute, Big Ass Truck, Don Dilego, Jeffrey Halford and the Healers, The Helio Sequence, Chris Lee, Mario Pavone Octet, Steve Vai, The Wild Seeds
- December 9, 2001
- Femi Kuti, Anton Barbeau, Boy Sets Fire, Randall Bramblett, Jeremy, Los Straitjackets, Ramona the Pest, Väsen, Paul McCartney tribute albums, Isley Brothers
- December 16, 2001
- Christmas music from Suzy Bogguss, The December People, The Green Pajamas, and Nancy Wilson. Plus albums from Belle De Gama, Sean Costello, The Dragons, Gutbucket, Rich McCulley, Nathan Mahl, Porterhouse Quintet, Saturnia
